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Poloxamer 188-Coated Ammonium Methacrylate Copolymer Nanocarriers Enhance Loperamide Permeability across Pgp-Expressing Epithelia

Poloxamer 188-Coated Ammonium Methacrylate Copolymer Nanocarriers Enhance Loperamide Permeability across Pgp-Expressing Epithelia

by Cendhy | Dec 1, 2020

Autores: Johanna Catalan-Figueroa, Mauricio A. García, Pilar Contreras, Constanza B. Boisset, Pablo M. Gonzalez, Jenny L. Fiedler, Mariela F. Pérez, Javier O. Morales. Loperamida es un agonista μ-opioide con baja absorción gastrointestinal, principalmente por su...
Angiotensin-(1–9) prevents cardiomyocyte hypertrophy by controlling mitochondrial dynamics via miR-129-3p/PKIA pathway

Angiotensin-(1–9) prevents cardiomyocyte hypertrophy by controlling mitochondrial dynamics via miR-129-3p/PKIA pathway

by Cendhy | Jul 31, 2020

Autores: Sotomayor-Flores, Cristian et al. El péptido Angiotensina-(1-9) participa de la vía metabólica no canónica del sistema renina-angiotensina, uno de los sistemas encargados de regular la presión sanguínea en el cuerpo humano. El péptido Ang-(1-9) tiene un...
Astaxanthin Counteracts Excitotoxicity and Reduces the Ensuing Increases in Calcium Levels and Mitochondrial Reactive Oxygen Species Generation

Astaxanthin Counteracts Excitotoxicity and Reduces the Ensuing Increases in Calcium Levels and Mitochondrial Reactive Oxygen Species Generation

by Cendhy | Jul 31, 2020

Autores: García, Francisca, et al. El pigmento carotenoide astaxantina (ASX) tiene fuertes propiedades antioxidantes. Hemos reportado previamente que ASX protege a las neuronas del efecto dañino de oligómeros β-amiloide, que promueven la producción excesiva de...
Anti hypertensive agents in patients with COVID-19. Revista Chilena de Cardiología (2020)

Anti hypertensive agents in patients with COVID-19. Revista Chilena de Cardiología (2020)

by Cendhy | May 20, 2020

Andrea Ramírez-Sagredo, Andrés Ramírez-Reyes, María Paz Ocaranza, Mario Chiong, Jaime A. Riquelme, Jorge E. Jalil, Sergio Lavandero. On December 31, 2019, the World Health Organization (WHO) was informed by the Chinese health authorities of the appearance of cases of...
Cardiac remodeling in experimental cardiac failure induced by hyperlipidemia in mice. Revista Chilena de Cardiología (2020).

Cardiac remodeling in experimental cardiac failure induced by hyperlipidemia in mice. Revista Chilena de Cardiología (2020).

by Cendhy | May 20, 2020

Alejandra Lonis, Jackeline Moya, Jorge Jalil, Maria Paz Ocaranza, Attilio Rigotti, Luigi Gabrielli. The objective of this research has been to characterize myocardial remodeling and to evaluate the survival associated with cardiac disease due to atheromatosis...
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Últimas publicaciones

  • CENDHY Director receives 2015 ASILFA Prize 4 January 2022
  • Most recent evidence on the use of ACE Inhibitors and ARBs on COVID-19 patients 20 September 2020
  • Pharmaceutical technology developed by CENDHY director is recognized in national innovation contest 20 September 2020
  • “Nanomedicine: small solutions for giant issues” 1 September 2020
  • CENDHY deputy director interviewed in hometown-based radio 21 August 2020
  • CENDHY researcher gives practical advice on how to improve cardiovascular health 17 August 2020
  • CENDHY researcher explains there is a direct link between COVID-19 and how hypertensive patients respond 28 July 2020
  • CENDHY director was interviewed on radio station from Punta Arenas 28 July 2020
  • Continuing education to the medical community: CENDHY participated in an online congress of the Chilean Society of Hypertension and SAVAL 21 July 2020
  • New research center on hypertension is established at the University of Chile 13 July 2020